Showing posts with label Cellulitis. Show all posts
Showing posts with label Cellulitis. Show all posts

Monday, January 7, 2013

Erysipelas of the Thigh and the Gluteal Region: Retrospective Multicenter Analysis of a Very Rare Entity in 39 Patients.


Erysipelas of the Thigh and the Gluteal Region: Retrospective Multicenter Analysis of a Very Rare Entity in 39 Patients.


**Editor's note: Not all infection we lymphers get can correctively be labled as cellulitis.  Often it is another form of infection referred to as erysipelas. This brief article is important specifically due to the closing line where it speaks of the disruption of the lymphatic vessels.  We know of course this can lead to secondary lymphedema**

Source

Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.

Abstract


Background: Erysipelas of the thigh and the gluteal region are rarely described and not well characterized. Therefore we aim to describe the prevalence, clinical characteristics, and risk factors of these erysipelas types. 

Methods: The files of 1,423 patients with erysipelas were analyzed. Data from patients with erysipelas of the thigh or the gluteal region were compared between the two groups and with a control group with erysipelas of the lower leg. 

Results: The thigh was exclusively affected in 2.1%, and the gluteal region in 0.6% of erysipelas patients. Gluteal erysipelas had conspicuous irregular borders and sometimes appeared bilaterally. Major risk factors for erysipelas of both sites were previous surgical interventions. Gluteal erysipelas was common in patients with the metabolic syndrome and required a more intense antibiotic therapy. 

Conclusion: Erysipelas of the thigh and the gluteal region are rare and significantly associated with prior surgical disruption of lymphatic vessels.


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Infections in Medicine

For further information:


Classification and External Resources
ICD-10A46.0 - 
Excludes:postpartum or puerperal erysipelas O86.8 )
ICD-9035 -Erysipelas (gangrenous) (infantile) (newborn) (phlegmonous) (suppurative) 035 
  • 035 is a specific code that can be used to specify a diagnosis
  • 035 contains 9 index entries

035 excludes:

  • postpartum or puerperal erysipelas (670)
DiseasesDB4428
MedlinePlus000618
eMedicinederm/129 
MeSHD004886

Wednesday, November 7, 2012

Incidence of deep vein thrombosis in erysipelas or cellulitis of the lower extremities.


Incidence of deep vein thrombosis in erysipelas or cellulitis of the lower extremities.


Aug 2012

Source

Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.

Abstract


The incidence of deep vein thrombosis (DVT) in patients with erysipelas and cellulitis of the lower extremities is unknown. As such, the indication and efficacy of prophylactic anticoagulation for prevention of DVT in these patients is unclear. The main goal of this review is to provide an estimate of the incidence of DVT in erysipelas and cellulitis based on existing literature. A comprehensive search of the electronic sources: MEDLINE, EMBASE, CINAHL, LILAC and Cochrane without any language limitation was performed from 1950 to April 2011 for articles focused on the occurrence of DVT in cellulitis or erysipelas of the lower extremities. The selected studies were divided into two groups according to presence or absence of systematic investigation for DVT. Those studies in which the patients received prophylactic or therapeutic anticoagulants before a diagnosis of DVT were excluded. The reported incidence rate of DVT in patients with erysipelas or cellulitis of the lower extremities is highly variable, ranging from 0 to 15%. In this review, the overall incidence rates of DVT in studies with and without systematic investigation for thromboembolism were 2.72% (95% CI: 1.71-3.75%) and 0.68% (95% CI: 0.27-1.07%), respectively. Given the low reported overall incidence of DVT, neither routine prophylactic anticoagulation nor systematic paraclinical investigation for DVT is indicated in low risk patients with erysipelas or cellulitis of the lower extremities. DVT should still be considered in patients with high pretest probability or other thromboembolic risk factors.

Wednesday, September 19, 2012

Erysipelas

Erysipelas


Key Words:  Strep A,  Lymphedema,  Cellulitis,  Bacteremia,  Septicemia, Cutaneous lympatics, immunocompromised,  St. Anthony's Fire,  Staph aureus,  Strep G, Penicillin,  Probenecid, Dicloxacillin,  Erythromycin,  Keflex,  Augmentin,  Necrosis,  Gangrene,  Thrombophebitis, Bacterial endocarditis,  Soft tissue infections




Discussion

Erysipelas (also called St. Anthony's Fire)is a superficial bacterial skin infection skin generally caused by (Strep A bacteria or Strep B bacteria. It can spread with alarming rapidity as it invades the cutaneous lymphatics.

While some classify it as a "form of cellulitis," it actually can be differentiated by the clear lines of demarcation of the infection. Symptoms include marked lines of infection, fever, pain, an overall achy feeling and swollen lymph nodes. Most cases involve the legs, and the second largest number of cases involve the face.  However a delay in treatment can result in deeper cellulitis or lymphangitis.

Like any type of infection a lymphedema patient experiences, antibiotic treatment needs to start immediately so as to prevent septicemia or bacteremiaAs with any infection erysipelas present a serious threat due to the immunocompromised state of the lymphedemous limb and because possible fibrosis handicaps effective antibiotic therapy. Also, in lymphedema patients Staph aureus (not Strep A) has been implicated as the infective bacteria.

While very similar and often confused with actual cellulitis it can be differentiated by the raised borders and advancing edges. The most commonly affected body areas are the legs, followed by the face.

Risk Factors

There are a number of factors that might predispose one to erysipelas.  The primary cause of course is a break, cut or entry foci in the skin and subsequent infection usually by a Strep A bacterium.  Susceptibility factors include edema, lymphedema, venous insufficiency, venous stasis, dermatosis, diabetes, HIV infection, and other immunocompromising medical conditions.
Transmission factors include port of entry through nasal cavity, insect bites, cut, incisions.

Symptoms

The infection may start out as a inconspicuous small red patch and spread rapidly to a painful fiery red plaque.  The infection area will be warm or hot and quite tender.  Over-all body symptoms might include feeling unusually drained of energy, achiness, chills, fever and malaise. There may also be blisters on the infected area and possible red streaking. 

Treatment

Treatment generally will involve the administration of an oral antibiotic.  The infection responds well to penicillin based antibiotic. In addition Probenecid may be used as it increase the effectiveness of penicillins. For more resistant infections dicloxacillin may be used.  Other antibiotics may include  NafcillinErythromycinKeflex and Augmentin 

Depending upon the severity and spread IV antibiotic therapy may also be used for lymphedema patients.  Also, limiting one's activity with limb elevation is standard protcol.

Blood cultures and/or wound cultures may be needed to determine the exact bacteria involved. 

Complications

Complications may include bacteremia or septicemia, abscess, tissue necrosis (gangrene)in the most severe cases, thrombophlebitisbacterial endorcarditis.

Prognosis

Prompt diagnosis and treatment will bring favorable results and in all but a very few patients recovery will be complete and without complications.  At risk groups, including those with lymphedema may experience recurrent episodes.

Full Text 





Wednesday, February 22, 2012

Cellulitis

Cellulitis

This is by far and wide, the most common infection lymphedema patients experience.

Discussion Acute Cellulitis

Acute Cellulitis is one of the complications of lymphedema. The patient may not be aware of the source of the etiology. Sometimes it may be a cut, mosquito bite, open wound or other infection in the body.


The first sign is increased or different quality of PAIN involving the lymphedema limb. The patients often describe this as a "flu like symptom or an ache" involving the Lymphedema arm or leg. This is usually followed by sudden onset of ERYTHEMA (redness, red streaks or blotches) on the involved limb. The HYPERTHERMIA (lymphedema limb becomes warm, hot) will follow and the patient may experience the CHILLS and even HIGH FEVER.


The early intervention and treatment with antibiotics will resolve this condition (it usually takes a very minimum ten day course of antibiotics). Only a Medical Doctor will be able to prescribe the Antibiotics, thus a consultation with a Doctor is necessary. Severe Cellulitis may require Intravenous Antibiotic treatment and hospitalization. Again, elevation of the affected limb is important.

During that phase the patient should NOT massage the lymphedema limb, bandage, apply the pump, wear tight elastic sleeve or exercise excessively. Avoid the blood pressure and blood to be drawn from the involved arm. Keep the limb elevated as much as possible while resting. Once the symptoms dissipate the treatment MLD/CDP should be initiated.


How do we prevent this infection? The patient should be careful with daily activities and take all precautions to protect the skin (wear gloves when gardening, cleaning with detergents, etc... ). If an injury to skin occurs on the lymphedema limb it is necessary to clean the wound with alcohol or hydrogen peroxide and apply Neosporin/Polysporin antibiotic ointment. If the symptoms progress seek the attention of a physician immediately.

It is so very important to avoid getting cellulitus as it further destroys the lymphatic system. Allowed to spread or continue it can become systemic and can lead to gangrene, amputation of the limb or even death.

Risk Factors

Cracks or peeling skin between the toes

History of peripheral vascular disease

Injury or trauma with a break in the skin (skin wounds)

Insect bites and stings animal bites, or human bites

Ulcers from certain diseases, including diabetes and

vascular disease

Use of corticosteroid medications or

medications that suppress the immune system

Wound from a recent surgery

Lymphedema


Clinical

Cellulitis is clinically a spreading infection involving both the dermis and subcutaneous tissues. Unlike erysipelas, it will not have a clear raised border. Other features may include red streaking from the infected area, regional lymphadenopathy.

Diagnosis

The basic way of diagnosing cellulitis is through a physical exam of the effected area, inconjunction with the above symptoms. Rememer, the area may be very red, warm to the touch, swollen and painful.

The doctor will also look for any cuts, scrapes, bites, ulcers or bruises, each is where bacteria could have entered the body.

Additional tests such as a blood test or culture may also be needed to determine the type of bacteria causing the infection.

Symptoms

Symptoms include all over body ache, fever, severe pain of the infected area, chills, weakness. The skin color will be red, warm and very tender to the touch.

Causes

The most common bacteria responsible for cellulitis infections are staph aureus and strep A. Other less common bacterial agents include Strep B, gram-negative bacteria, and immunocompromised patients pneumococcus. Less common bacteria such as Hemophilus influenzae, Pasturella multocide, and erysipelothrix rhusiopathiae can cause it as well.

Entry foci for the bacteria includes nasal cavities, wound, cuts, scrapes (any type of skin break). Insect bites (especially spider) can cause the condition. Cat scratches, animal bites are another source of bacteria.

Treatment

Cellulitis responds well to antibiotic therapy. Generally, a ten day course of treatment is prescribed. Antibiotics used to treat cellulitis include Keflex, Augmentin, penicillins. Unasyn and vancomycin are standard IV antibiotics. In situations of a gram negative infection, Gentamicin is used. The types of antibiotic treatments include oral, topical (for a wound or skin cut) and intravenous antibiotics. Often it is only the IV antibiotic that can actually penetrate the fibrotic lympedema tissue to reach the bacteria.

For special at risk patients, blood work may also be indicated to assure the infection has not become systemic.

This group, which includes lymphedema patients may need extended IV antibiotic therapy. Lymphedema patients also need to elevate the effected limb, stop using compression garments and/or bandages until the infection has cleared.

See also: Lymphedema and Cellulitis

ICD9 - ICD10 - Related Resource Information

ICD-10L03. -
ICD-92008 ICD-9-CM Diagnosis 682.9

Cellulitis and abscess of unspecified sites

  • 682.9 is a specific code that can be used to specify a diagnosis
  • 682.9 contains 27 index entries
  • View the ICD-9-CM Volume 1 682.* hierarchy

682.9 also known as:

  • Abscess NOS
  • Cellulitis NOS
  • Lymphangitis, acute NOS

682.9 excludes:

DiseasesDB29806
eMedicinemed/310 emerg/88 derm/464
MeSHD002481

Tuesday, February 14, 2012

Lymphedema infections

I feel it is important to have an understanding of the various types of infections that we face with lymphedema. These infections include cellulitis, lymphangitis, and erysipelas. An extensive list follows below.
One must remember that every infection we have further damages our lymphatics, thus leading to more severe lymphedema. Untreated infection will lead to sepsis (commonly refered to as blood poisoning), gangrene which involves loss of limb and/or eventual death.
In treating any type of infection, the doctor not only must identify the type of bacteria involved, but must understand the staging of lymphedema and the differences in the tissue types of the stages.
Heavily fibrotic lymphedema limbs are exceedingly difficult to treat because the denseness of the tissue impeeds or even can prevent the chosen antibiotic from reaching the bacteria. In this situation long term IV antibiotic thereapy should be considered.
I will be doing posts on all the related infections. We need to remember (as does the doctor), that a limb with lymphedema is a localized immunosuppressed area, which means in practical terms that any infection has the potential of agressive spread and can quickly become life threatening.
The most common bacterial infections that lymphedema patients have difficulties with includes:
Necrotizing Fascilitis (Flesh eating bacteria)
Other important related pages relating to infections include:
Lymphadenopathy - Information on swollen lymph nodes
Blisters - Improper care of a simple boil can lead to severe consequences.
These pages give helpful information relating to treatment, prevention, and doctr care:
Antibiotics - Everyone should also have an updated list of medicines, doses and doctors prescribing the medicine.
Probiotics - Helpful in replacing the "good" bacteria that antibiotics kill.
Infectious Disease Doctor - The type of doctor who is best trained to treat and understand infections. I recommend that we all have one.
Feb 14 ,2012